Mesembrine (Kanna Extract)
Mesembrine (Kanna Extract)
Mesembrine, derived from Kanna (Sceletium tortuosum), is a naturally occurring alkaloid known for its powerful mood-enhancing and cognitive-boosting effects. Kanna has been traditionally used in South Africa for centuries, primarily for its anxiolytic (anti-anxiety) and mood-elevating properties. Mesembrine specifically acts as a serotonin reuptake inhibitor (SRI), meaning it increases serotonin levels in the brain, which contributes to improved mood, reduced anxiety, and enhanced mental clarity.
Mesembrine's role as a serotonin modulator makes it particularly effective for individuals who experience stress or anxiety during workouts. Elevated serotonin levels can lead to a calmer, more focused mental state, allowing for better concentration and performance, especially during high-intensity exercise sessions. It has also been shown to have adaptogenic properties, helping the body adapt to stress, which can be beneficial in both physical and mental performance. This means that athletes may experience less mental fatigue and stress during workouts, leading to improved endurance and a more enjoyable training experience.
In addition to its mental benefits, Mesembrine has been suggested to improve cognitive function and reaction times. By increasing serotonin and other key neurotransmitters, it promotes greater cognitive flexibility, making it easier to stay focused and mentally agile during complex tasks or prolonged workouts. For individuals involved in competitive sports or activities that require quick decision-making, this cognitive boost can provide a significant edge.
Another advantage of Mesembrine is its ability to enhance mood without causing overstimulation. Unlike stimulants like caffeine, which can sometimes lead to jitters or energy crashes, Mesembrine promotes a calm yet alert mental state, making it an ideal addition to pre-workout supplements that are designed to enhance focus and performance without overwhelming the nervous system. However, because of its effects on serotonin levels, it’s important to avoid combining Mesembrine with other serotonin-boosting compounds to prevent any potential imbalances.
Sources:
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4296158/
- https://www.frontiersin.org/articles/10.3389/fphar.2021.752883/full
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651136/
- https://pubmed.ncbi.nlm.nih.gov/24078953/
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